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| Registros recuperados: 25 | |
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| LEMUS,DAVID; DABANCENS,ALFREDO; ILLANES,JULIO; FUENZALIDA,MARCELA; GUERRERO,ANIBAL; LÓPEZ,CLAUDIA. |
| Tumor growth is the result of combined cell proliferation overwhelming cell death and neoangiogenesis. This report shows CAM angiogenesis promoted by TA3 tumor supernatant with or without low dosis of betamethasone (Minimal antiangiogenic concentration: ß-MAAC). Methylcellulose discs instilled with 10 µl of ß-MAAC (0.08 µg/ml),10 µl of tumor supernatant(TA3ts),5 µl ß-MAAC + 5 µl TA3ts, and 10 µl of PBS as control were implanted in host chick eggs. On day 12, the grafts were removed, photographed and fixed. Sections were stained in parallel, one and three with hematoxylin-eosin, and section two by the Tunel method. The number of vessels was evaluated in a microscopic field of the CAM (2250 µm2 ). The results show that ß-MAAC produced a significant... |
| Tipo: Journal article |
Palavras-chave: Antiangiogenesis; Betamethasone; CAM; Tumor. |
| Ano: 2001 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602001000300010 |
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| Ahmad,Sajjad; Ullah,Farhat; Ayaz,Muhammad; Zeb,Anwar; Ullah,Farman; Sadiq,Abdul. |
| BACKGROUND: Cancer, being the foremost challenge of the modern era and the focus of world-class investigators, gargantuan research is in progress worldwide to explore novel therapeutic for its management. The exploitation of natural sources has been proven to be an excellent approach to treat or minify the excessive angiogenesis and proliferation of cells. Similarly, based the ethnomedicinal uses and literature survey, the current study is designed to explore the anti-tumor and anti-angiogenic potentials of Rumex hastatus. Anti-tumor and anti-angiogenic activities were carried out using potato-disc model and chorioallantoic membrane (CAM) assay respectively. Moreover, R. hastatus was also assessed for antibacterial activity against Agrobacterium... |
| Tipo: Journal article |
Palavras-chave: Rumex hastatus; Agrobacterium tumefaciens; Saponins; Angiogenesis; Tumor. |
| Ano: 2016 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602016000100018 |
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| Daleck,Carlos Roberto; Franceschini,Paulo Henrique; Alessi,Antonio Carlos; Santana,Áureo Evangelista; Martins,Maria Izabel Mello. |
| As neoplasias mamárias em cadelas representam importante parcela das neoplasias em cães, merecendo atenção dos pesquisadores quanto ao diagnóstico, tratamento e prognóstico. No presente trabalho, 23 cadelas de várias raças ou cruzamentos, com idades entre 8 e 11 anos portadoras de neoplasia mamária foram estudadas. Doze eram multíparas, 6 primíparas e 5 nulíparas. Todas eram da região de Jaboticabal, SP, atendidas no Hospital Veterinário da FCAVJ-UNESP. Os animais foram avaliados clínica e radiolagicamente e submetidos à punção aspirativa da massa anormal de tecido, com agulha fina. Dessa mesma massa foi também retirado, cirurgicamente, um fragmento para exame histopatológico. A maior incidência foi de carcinoma (52,17%), seguidos por tumores mistos... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cão; Tumor; Mama; Quimioterapia; Cirurgia. |
| Ano: 1998 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84781998000100016 |
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| Rosas,Carlos; Sinning,Mariana; Ferreira,Arturo; Fuenzalida,Marcela; Lemus,David. |
| BACKGROUND: During the last few years it has been shown in several laboratories that Celecoxib (Cx), a non-steroidal anti-inflammatory agent (NSAID) normally used for pain and arthritis, mediates antitumor and antiangiogenic effects. However, the effects of this drug on a tumor cell line resistant to chemotherapeutical drugs used in cancer have not been described. Herein we evaluate the angiogenic and antitumor effects of Cx in the development of a drug-resistant mammary adenocarcinoma tumor (TA3-MTXR). RESULTS: Cx reduces angiogenesis in the chick embryonic chorioallantoic membrane assay (CAM), inhibits the growth and microvascular density of the murine TA3-MTXR tumor, reduces microvascular density of tumor metastases, promotes apoptosis and reduces... |
| Tipo: Journal article |
Palavras-chave: Angiogenesis; Celecoxib; Tumor. |
| Ano: 2014 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602014000100027 |
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| Pinto,A.C.B.C. Fonseca; Villamizar,L.A.; Ghirelli,C.O.; Silva,T.R.C.; Baroni,C.O.; Banon,G.P.R.; Guerra,J.M.; Amaral,C.T.; Torres,L.N.. |
| Among the tumors affecting the choroid plexus in dogs, the papilloma ranks second place in incidence after cell carcinoma tumors. Presumptive diagnosis can be made through imaging methods, such as computed tomography and magnetic resonance images. Definitive diagnosis of plexus choroid tumor is based on histopathological findings. This report presented the tomographic features of the brain in a 6-year-old intact female Rottweiler with choroid plexus papilloma. The computed tomography showed right lateral ventricle enlargement, midline deviation and an enhanced mass into the postcontrast phase. At necropsy, a mass on the floor of the right lateral ventricle was observed, associated with important ventricle dilatation. The histopathological analysis... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Dog; Computed tomography; Choroid plexus; Tumor. |
| Ano: 2013 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352013000300023 |
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| Faria,A.V.; Macedo Jr.,F.C.; Marsaioli,A.J.; Ferreira,M.M.C.; Cendes,F.. |
| High resolution proton nuclear magnetic resonance spectroscopy (¹H MRS) can be used to detect biochemical changes in vitro caused by distinct pathologies. It can reveal distinct metabolic profiles of brain tumors although the accurate analysis and classification of different spectra remains a challenge. In this study, the pattern recognition method partial least squares discriminant analysis (PLS-DA) was used to classify 11.7 T ¹H MRS spectra of brain tissue extracts from patients with brain tumors into four classes (high-grade neuroglial, low-grade neuroglial, non-neuroglial, and metastasis) and a group of control brain tissue. PLS-DA revealed 9 metabolites as the most important in group differentiation: γ-aminobutyric acid, acetoacetate, alanine,... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Brain; Tumor; Magnetic resonance spectroscopy; Spectroscopy; Metabolism. |
| Ano: 2011 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0100-879X2011000200009 |
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| Rosas C,Carlos; Roa,Ignacio; Sinning O,Mariana; Fuenzalida B,Marcela; Lemus A,David. |
| En el estudio del cáncer, se utilizan diversas líneas celulares, cada una de ellas con características propias. Una de esas líneas tumorales es la variante multirresistente a drogas del tumor TA3. Si bien, existen diversos estudios con esta línea tumoral, no existe una descripción morfológica detallada de esta, ni tampoco que se observe el efecto del Celecoxib, un inhibidor de COX-2 sobre este tejido. Se usaron 18 ratones divididos en 3 grupos, los cuales recibieron: Inoculación de PBS; inoculación de células tumorales TA3; inoculación de células tumorales + tratamiento con Celecoxib (1000 ppm), respectivamente. Los ratones fueron sacrificados y procesados histológicamente para ser teñidos con H&E, PAS y Arteta. El estudio reveló que tumor muestra una... |
| Tipo: Journal article |
Palavras-chave: Tumor; Angiogénesis; Celecoxib. |
| Ano: 2013 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0717-95022013000200005 |
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| ZÚÑIGA,JORGE; FUENZALIDA,MARCELA; GUERRERO,ANÍBAL; ILLANES,JULIO; DABANCENS,ALFREDO; DÍAZ,EUGENIA; LEMUS,DAVID. |
| Angiogenesis, the development of new blood vessels from the existing vascular network, may result as a consequence of the increase or decrease of proangiogenic or antiangiogenic factors, respectively. The tumor itself could up-regulate the production of angiogenic factors. Recently, we established that the steroidal drug betamethasone in low concentration inhibit the neovascularization promoted by TA3 Ts on CAM of chick embryos. We describe here the effects of the non-steroidal drug ketoprofen, alone or in association with betamethasone, on the angiogenesis promoted by TA3 Ts on CAM. The main finding reported here is that the formation of new blood vessels is strongly inhibited by low concentrations of ketoprofen. The association of both drugs produced a... |
| Tipo: Journal article |
Palavras-chave: Angiogenesis; Antiangiogenesis; Tumor; Betamethasone; Ketoprofen. |
| Ano: 2003 |
URL: http://www.scielo.cl/scielo.php?script=sci_arttext&pid=S0716-97602003000200013 |
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| Teixeira,Pedro Paulo Maia; Souza,Erica Siqueira; Jark,Paulo César; Coutinho,Leandro Nassar; Silva,Alanna do Socorro Lima da; Guiduce,Marcos Vinicius Sicca; Maria,Bruna Piva; Silva,Paloma Espirito Santo; Semolin,Lívia Maria Souza; Silva,Marco Augusto Machado; Vicente,Wilter Ricardo Russiano; Tinucci-Costa,Mirela; Nardi,Andrigo Barboza De. |
| Laryngeal and tracheal tumors are rare in pets; some piece of information on their disease behavior, therapy and evolution are limited. Neoplasms in this area are a diagnostic challenge. In many cases, they can be biopsied and excised using endoscopic instruments, but there is no report of this in canines. The goal of this study is to report a successful case of a laryngeal neoplasm removal through endoscopy. A head and neck radiogram revealed a mass in the laryngeal lumen protruding into the trachea. The patient then underwent an endoscopy to confirm the radiographic diagnosis and to surgically remove the tumor. The histopathological diagnosis was poorly differentiated carcinoma. The most appropriate treatment for laryngeal tumors is the resection of the... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Tumor; Larynx; Canine; Endoscopy. |
| Ano: 2015 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782015000100131 |
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| Prado,L.O.C.; Franco,G.G.; Legatti,E.; Ranzani,J.J.T.; Quitzan,J.G.; Siqueira,E.G.M.; Souza,J.A.L.; Minto,B.W.; Brandão,C.V.S.. |
| RESUMO Os tumores do sistema digestório não são comuns na medicina veterinária e as neoplasias de estômago representam menos de 1% de todos os tumores malignos. O leiomiossarcoma é o segundo tumor que mais acomete o trato gastrointestinal de cães, com predisposição para as regiões de jejuno e ceco, mas qualquer porção pode ser afetada, desde o esôfago até o reto. O presente trabalho relata um caso em um canino da raça Shar-pei, macho, com 13 anos de idade e histórico de episódios eméticos pós- prandiais e emagrecimento progressivo havia oito meses. Após avaliação radiográfica e endoscópica, foi indicada intervenção cirúrgica e observada tumoração gástrica associada a hérnia de hiato. O diagnóstico de leiomiossarcoma gástrico foi estabelecido por meio de... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Cirurgia; Estômago; Oncologia; Tumor. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352017000100111 |
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| Ferreira,M.G.P.A.; Antunes,A.V.; Pascoli,A.L.; Nazaret,T.L.; Gering,A.P.; Reis Filho,N.P.; Costa,M.T.; Nardi,A.B.. |
| ABSTRACT Neuropathic pain occurs when there is a lesion or a dysfunction of the nervous system. Humans and veterinary patients may develop neuropathic pain, but in veterinary it is not often reported probably because of its mistaken diagnosis. A canine patient was admitted to the Veterinary Hospital of UNESP-Jaboticabal-SP, Brazil with a nodule on the left thoracic limb. The nodule was surgically removed, and histopathological analysis demonstrated the tumor was a soft tissue sarcoma (STS) and the margins were not clean. Based on the patient’s health condition and the lack of suitable equipment, the next procedure was limb amputation. The patient received analgesic medication in the post-surgery period; nevertheless, clinical signs of neuropathic pain were... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Analgesia; Oncology; Phantom limb; Radiotherapy; Tumor. |
| Ano: 2019 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0102-09352019000401116 |
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| Pliego,Cristina Mendes; Ferreira,Maria de Lourdes Gonçalves; Ferreira,Ana Maria Reis; Chaudon,Marília Botelho de Oliveira. |
| A biópsia com agulha de corte é um método fácil e rápido para obtenção de um fragmento do tumor, e amplamente utilizado no diagnóstico de lesões mamárias em mulheres. O objetivo do estudo foi realizar a avaliação diagnóstica da biópsia em 26 nódulos mamários de 19 cadelas, utilizando a agulha de corte Super-core II® 14-ga x 9cm. Após a biópsia, os pacientes foram submetidos à mastectomia para obtenção dos nódulos mamários. As amostras da biópsia e os nódulos foram analisados histopatologicamente e as neoplasias foram classificadas segundo a Organização Mundial de Saúde (OMS). A biópsia com agulha mostrou sensibilidade de 100% e especificidade de 71,4% no diagnóstico de adenocarcinomas, e no diagnóstico de carcinossarcomas mostrou 71,4% de sensibilidade e... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Biópsia com agulha de corte; Tumor; Mama. |
| Ano: 2008 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782008000800018 |
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| Mesquita,Leonardo Pereira; Mesquita Neto,Francisco Duque de; Varaschin,Mary Suzan; Wouters,Angélica Terezinha Barth; Wouters,Flademir. |
| ABSTRACT: Renal cell carcinoma, especially with extensive involvement of peritoneal cavity, is rarely described in horses. This study described a case of renal cell carcinoma in an 8-year-old mare, which presented with an enlargement in the left flank, decreased appetite and straining to defecate. Clinically, a tumor in the left retroperitoneal space was detected by rectal examination and ultrasonography. The animal died after one month of clinical evolution. At necropsy, the left kidney was completely effaced by a 50cm in diameter, irregular, round, lobulated cystic mass with necro-hemorrhagic areas. Within the peritoneal cavity, there was severe hemoperitoneum and numerous sessile and pedunculated masses ranging from 2.0 to 15.0cm diameter that were... |
| Tipo: Info:eu-repo/semantics/article |
Palavras-chave: Equine; Renal neoplasia; Pathology; Kidney; Tumor. |
| Ano: 2017 |
URL: http://www.scielo.br/scielo.php?script=sci_arttext&pid=S0103-84782017000100602 |
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| Registros recuperados: 25 | |
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